Dynamic changes in serum IL-6, TNF-α, and β₂-microglobulin as early predictors of post-treatment relapse in lymphoma: a prospective cohort study
Longitudinal monitoring of IL-6, TNF-<i>α</i>, and β₂-MG identifies early inflammatory trajectories linked to lymphoma relapse. IL-6 and β₂-MG at 3 months post-chemotherapy are independent and robust predictors, and a multi-marker model markedly enhances early-warning performance.
Authors
- Chunmeng Song
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Jianqiang Song
- Yuhao Ma
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3389/fmed.2026.1750664
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00