Inference of SARS-CoV-2 exposure biomarkers using large-scale T-cell repertoire profiling
This developed classifier is applicable to individual TCR repertoires obtained using various protocols, paving the way to AIRR-seq-based immune status assessment in large cohorts of donors.
Authors
- Olga V. Britanova (ORCID: https://orcid.org/0000-0002-6295-1392)
- Elizaveta K. Vlasova
- S. M. Yudin (ORCID: https://orcid.org/0000-0002-7942-8004)
- Anton А. Keskinov (ORCID: https://orcid.org/0000-0001-7378-983X)
- Anastasia Pivnyuk
- Denis Rebrikov (ORCID: https://orcid.org/0000-0002-1884-1807)
- В. В. Макаров (ORCID: https://orcid.org/0000-0001-9495-0266)
- V. S. Yudin (ORCID: https://orcid.org/0000-0002-9199-6258)
- Mark Izraelson (ORCID: https://orcid.org/0000-0001-8606-9575)
- Ilgar Z. Mamedov (ORCID: https://orcid.org/0000-0002-3992-9285)
- Mikhail Shugay (ORCID: https://orcid.org/0000-0001-7826-7942)
- Sergey I. Mitrofanov (ORCID: https://orcid.org/0000-0003-0358-0568)
- P. V. Shelyakin
- Alexander Komkov (ORCID: https://orcid.org/0000-0001-9113-698X)
- Dmitriy Chudakov (ORCID: https://orcid.org/0000-0001-6273-4008)
- Darya Korneeva
- Alexandra I. Nekrasova
- Veronika I. Skvortsova
- Ekaterina A. Snigir
Institutions
- ITMO University (RU)
- Emirates Foundation (AE)
- Pirogov Russian National Research Medical University (RU)
- Institute of Bioorganic Chemistry (RU)
- Federal Agency for Health and Social Development (RU)
- Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology (RU)
- Institute of Bioorganic Chemistry (BY)
- Federal Medical-Biological Agency (RU)
Publication Details
- Journal
- Genome Medicine
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1186/s13073-025-01589-4
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation