Clopidogrel Dosing Scheme in Pediatric Cardiac Patients 0-24 Months Old Using P2Y<sub>12</sub> Reaction Unit Monitoring.
Pediatric cardiac patients may require a gradual escalation of clopidogrel dosing with age, in contrast to the static low dose recommended by the PICOLO trial during the first 24 months of life. An age-based dosing scheme may prove beneficial for this age group. Prospective studies evaluating age-based clopidogrel dosing in this patient population could offer further insight into this relationship.
Authors
- Kathryn M. DeAvilla
- Mario Briceno-Medina (ORCID: https://orcid.org/0000-0003-4461-2175)
- Carli Coalter (ORCID: https://orcid.org/0000-0001-7738-3028)
- Benjamin W. Kozyak (ORCID: https://orcid.org/0000-0002-4809-0960)
- Mark Rayburn
- Pilar Anton-Martin
- Meredith Ray
Institutions
- Children's Hospital of Philadelphia (US)
- Medical City Children's Hospital (US)
- Le Bonheur Children's Hospital (US)
- University of Memphis (US)
Publication Details
- Journal
- PubMed
- Published
- 2026-02-01
- DOI
- https://doi.org/10.5683/jppt-25-00024
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00