Sufentanil increases delirium risk compared to fentanyl in elderly perioperative ischemic stroke patients: a retrospective cohort study
In elderly patients with PIS, intraoperative fentanyl use was associated with a significantly lower risk of POD compared with sufentanil. Opioid selection may represent a modifiable risk factor in this high-risk population, offering an opportunity to improve anesthetic management and postoperative outcomes.
Authors
- Mengyao Qu
- Yingfu Li
- Weidong Mi (ORCID: https://orcid.org/0000-0002-3546-0440)
- MD Yulong Ma
- Miao Sun (ORCID: https://orcid.org/0000-0002-3074-8330)
- Yixun Lu
- Yanan He
- Rui Wang
- Huikai Yang
- Peng Li
- Hang Guo
- Yuxiang Song
Institutions
- Chinese PLA General Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-12
- DOI
- https://doi.org/10.3389/fmed.2026.1770366
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China