Correlation analysis between growth heterogeneity and genetic mutations in resected subsolid lung adenocarcinoma based on long-term computed tomography (CT) follow-up

Growing SSNs during identified on CT follow-up were significantly correlated with IA and EGFR mutations. EGFR may serve as a pivotal gene in driving the growth of SSNs; however, it is not a key gene in regulating their growth rate. This finding may help promote personalized management for SSN patients and uncover potential biomarkers and therapeutic targets with value.