An explainable deep learning framework for biosensing data interpretation in biomedical engineering and real-time health diagnostics

Evaluations on four biosensing datasets show that our framework achieves superior diagnostic accuracy (up to 92.48%) and AUC (up to 93.65%), outperforming several transformer-based baselines such as RoBERTa and T5. Furthermore, the model provides transparent uncertainty estimates, making it suitable for deployment in clinical and wearable scenarios. By integrating physiological semantics and model interpretability, our framework bridges the gap between black-box AI and trustworthy biomedical intelligence.

Authors

Institutions

Publication Details

Journal
Frontiers in Bioengineering and Biotechnology
Published
2026-02-12
DOI
https://doi.org/10.3389/fbioe.2025.1688586
Primary Topic
Explainable Artificial Intelligence (XAI)
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

An explainable deep learning framework for biosensing data interpretation in biomedical engineering and real-time health diagnostics

Weihong Huang, Heng Zhang, Zheng Yang
Frontiers in Bioengineering and Biotechnology
Explainable Artificial Intelligence (XAI)
article

An explainable deep learning framework for biosensing data interpretation in biomedical engineering and real-time health diagnostics

Weihong Huang, Heng Zhang, Zheng Yang
article en

Abstract

Evaluations on four biosensing datasets show that our framework achieves superior diagnostic accuracy (up to 92.48%) and AUC (up to 93.65%), outperforming several transformer-based baselines such as RoBERTa and T5. Furthermore, the model provides transparent uncertainty estimates, making it suitable for deployment in clinical and wearable scenarios. By integrating physiological semantics and model interpretability, our framework bridges the gap between black-box AI and trustworthy biomedical intelligence.

Frontiers in Bioengineering and BiotechnologyVol. 13
Central South University (CN), China Mobile (China) (CN), Chinese University of Hong Kong, Shenzhen (CN), National Clinical Research (US), Health Data Research UK (GB), Artificial Intelligence in Medicine (Canada) (CA)
Openalex Percentile: Top 59%
Explainable Artificial Intelligence (XAI)
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.