How threshold customisation affects the performance of a multiclass X-ray AI model for primary care triage: a retrospective study

Threshold optimisation is critical for adapting AI models to context-specific clinical workflows. Our study shows that adjusting the operating threshold enabled prioritisation of sensitivity and NPV, supporting safe AI-assisted triage in primary care. This is a deeply collaborative process that must involve radiology and clinical teams: selecting appropriate thresholds aligned with clinical objectives for safe and effective implementation. Future work will assess real-world operational impact and user acceptance following prospective deployment.

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Publication Details

Journal
BMJ Open
Published
2026-02-01
DOI
https://doi.org/10.1136/bmjopen-2025-111127
Primary Topic
COVID-19 diagnosis using AI
Type
article
Field-Weighted Citation Impact
0.00

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article

How threshold customisation affects the performance of a multiclass X-ray AI model for primary care triage: a retrospective study

Alvin Yong Quan Soon, Jia Lu Lilian Lin, Qi Wei Fong, Jordan Sim et al.
BMJ Open
COVID-19 diagnosis using AI
article

How threshold customisation affects the performance of a multiclass X-ray AI model for primary care triage: a retrospective study

Alvin Yong Quan Soon, Jia Lu Lilian Lin, Qi Wei Fong, Jordan Sim, Lay Wai Khin, Cher Heng Tan, Sreejith Balakrishnan, Sabrina Wong, Timothy Lin
article en

Abstract

Threshold optimisation is critical for adapting AI models to context-specific clinical workflows. Our study shows that adjusting the operating threshold enabled prioritisation of sensitivity and NPV, supporting safe AI-assisted triage in primary care. This is a deeply collaborative process that must involve radiology and clinical teams: selecting appropriate thresholds aligned with clinical objectives for safe and effective implementation. Future work will assess real-world operational impact and user acceptance following prospective deployment.

BMJ OpenVol. 16(2)
Tan Tock Seng Hospital (SG), SingHealth Polyclinics (SG), Singapore-MIT Alliance for Research and Technology (SG)
National Health Insurance Service
Reduced inequalities
Openalex Percentile: Top 58%
COVID-19 diagnosis using AI
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