Targeting NLRP3 inflammasome: a novel strategy for improving immune checkpoint inhibitor-associated pneumonitis
This study provides the first evidence that NLRP3 inflammasome activation constitutes a key upstream mechanism in CIP pathogenesis, offering novel therapeutic strategies for targeted intervention.
Authors
- Mei-Cen Liu
- Yahui Lv
- Xiaoran Cui (ORCID: https://orcid.org/0000-0002-9231-5012)
- Peng-Fei Cui
- Yin-Min Ji
- Yi-Heng Lu
- Yan Liu
- Yi Dong
- Yi Hu
- Tao Li
- Shu-Yan Xiao
Institutions
- Second Military Medical University (CN)
- Anhui Medical University (CN)
- Chinese PLA General Hospital (CN)
- Changchun Institute of Optics, Fine Mechanics and Physics (CN)
- First Affiliated Hospital of Chinese PLA General Hospital (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- Translational Lung Cancer Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.21037/tlcr-2025-aw-1240
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00