Negative interactions between Toscana virus and Leishmania infantum limit coinfection in sand flies
Our findings suggest competitive interactions between TOSV and L. infantum in sand flies, providing the first experimental indication of pathogen-pathogen interference within a natural vector. Such competition likely contributes to the rarity of coinfected sand flies in field surveys and highlights the importance of considering vector-level interactions when assessing transmission risks in endemic regions.
Authors
- Nikola Polanská (ORCID: https://orcid.org/0000-0002-5142-5880)
- Magdalena Jančářová (ORCID: https://orcid.org/0000-0003-0273-3446)
- Sophie Desloire
- M Stejskalová
- Maxime Ratinier (ORCID: https://orcid.org/0000-0003-2271-3549)
- Petr Volf
Institutions
- Université Claude Bernard Lyon 1 (FR)
- École Pratique des Hautes Études (FR)
- Charles University (CZ)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1186/s13071-025-07237-5
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00