Antimicrobial peptide chensinin‐1b attenuates <scp>T2DM</scp> progression in atherosclerotic <i>ApoE</i> <sup> <i>−/−</i> </sup> mice
In ApoE<sup>-/-</sup> mice, prolonged atherosclerotic pathology is associated with T2DM development. The antimicrobial peptide chensinin-1b attenuates AS and improves metabolic parameters, indicating potential multitarget intervention capabilities. These findings identify chensinin-1b as a candidate molecule for preventing AS-related metabolic abnormalities.
Authors
- Zhenjia Li
- Fan Fan (ORCID: https://orcid.org/0000-0003-1463-3610)
- Dong Shang (ORCID: https://orcid.org/0009-0006-2488-5503)
- Zhongpeng Qiu
- Yue Sun
Institutions
- Liaoning Normal University (CN)
Publication Details
- Journal
- Diabetic Medicine
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1111/dme.70232
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China