Evaluation of three syphilis algorithms: resolving discordance to ensure diagnostic accuracy
The reverse algorithm 2 is recommended, as the confirmation of TP-ECLIA by TPPA reduces the underdiagnosis of previously treated syphilis compared with the traditional algorithm and compensates for the limited specificity of TP-ECLIA, thereby representing an improvement over reverse algorithm 1.
Authors
- Yuanfang Wang
- Fei Ye (ORCID: https://orcid.org/0000-0003-0837-232X)
- Dongdong Li (ORCID: https://orcid.org/0000-0002-0290-6485)
- Sirui Wu
- L L Luo
- Yike Huang
- Jielun Deng
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Sexually Transmitted Infections
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1136/sextrans-2025-056643
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00