Exploring the mechanism of the Lianshi Jianpi formula in treating impaired glucose tolerance: a network pharmacology, molecular docking, and experimental validation study.
These findings reveal the potential of LSJPF as an IGT intervention that targets the AMPK/PI3K/AKT cascade, validating network pharmacology predictions and highlighting the role of multipathway mechanisms in metabolic diseases.
Authors
- Mio Jiang
- Yanbin Liang
- Binhua Ye (ORCID: https://orcid.org/0009-0009-3811-1906)
- Chen QIU
- Tong Wang
- Bowei HUANG
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2026-02-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.2026.01.015
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00