Rezafungin exhibits anti-biofilm properties against fungal biofilms <i>in vitro</i>

Together, these data show that rezafungin is non-inferior to caspofungin in terms of anti-biofilm activity and displays characteristics that suggest it can control biofilms more effectively than caspofungin. Further evaluation is required to establish whether these in vitro effects translate clinically, but the data indicate an opportunity for rezafungin to be used for the clinical management of biofilm-related diseases.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2026-02-04
DOI
https://doi.org/10.1093/jac/dkag058
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
0.00
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article

Rezafungin exhibits anti-biofilm properties against fungal biofilms in vitro

Hafsa Abduljalil, Gordon; id_orcid 0000-0002-0932-3514 Ramage, Riina Rautemaa-Richardson, Kerry; id_orcid 0000-0003-3037-5295 Bartie et al.
Journal of Antimicrobial Chemotherapy
Antifungal resistance and susceptibility
article

Rezafungin exhibits anti-biofilm properties against fungal biofilms in vitro

Hafsa Abduljalil, Gordon; id_orcid 0000-0002-0932-3514 Ramage, Riina Rautemaa-Richardson, Kerry; id_orcid 0000-0003-3037-5295 Bartie, Ryan Kean, Abhijit M. Bal, Craig Williams
article en

Abstract

Together, these data show that rezafungin is non-inferior to caspofungin in terms of anti-biofilm activity and displays characteristics that suggest it can control biofilms more effectively than caspofungin. Further evaluation is required to establish whether these in vitro effects translate clinically, but the data indicate an opportunity for rezafungin to be used for the clinical management of biofilm-related diseases.

Journal of Antimicrobial ChemotherapyVol. 81(4)
Glasgow Caledonian University (GB), Royal Lancaster Infirmary (GB), Manchester Academic Health Science Centre (GB), Glasgow Royal Infirmary (GB), Manchester University NHS Foundation Trust (GB), Wythenshawe Hospital (GB), NIHR Manchester Biomedical Research Centre (GB)
Good health and well-being
Openalex Percentile: Top 57%
Antifungal resistance and susceptibility
DOIOpen Access PDFOpenAlex
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Rezafungin exhibits anti-biofilm properties against fungal biofilms <i>in vitro</i> — Hafsa Abduljalil, Gordon; id_orcid 0000-0002-0932-3514 Ramage, et al. · Journal of Antimicrobial Chemotherapy (2026) | TGRS Research Map | TGRS