A blended digital therapy for depression in people with acquired brain injury: A feasibility and acceptability study

Depression following Acquired Brain Injury (ABI) is common, persistent and debilitating, yet access to psychological treatment is limited. Digital therapies, provided alongside clinician support, may help overcome these barriers. This study evaluated the feasibility, acceptability, and potential benefits of a blended intervention for depression post-ABI, using a mixed-method approach. Individuals with ABI and depression were offered a 4-week intervention (<i>MyACTION</i>), delivered via a novel smartphone app, alongside weekly video therapy sessions. Measures of depression, anxiety, and self-efficacy were collected pre- and post-intervention. Feasibility was evaluated through recruitment, retention, engagement, and usability ratings. Acceptability was assessed via post-treatment interviews. Initial indication of benefit was evaluated through change in scores in outcome measures. Twenty-one individuals consented, 19 completed the intervention, and 18 completed post-intervention interviews. On average, 82% of daily app tasks were completed. Overall, the app received "good" usability ratings. Barriers and facilitators to engagement were (1) health status, (2) motivation, (3) perceived utility, (4) usability, (5) accessibility, and (6) timing. Reductions in depression and anxiety were observed post-intervention. <i>MyACTION</i> was feasible and acceptable for individuals with ABI and depression. High engagement and positive feedback suggest blended digital approaches may help increase access to psychological support in this population.

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Publication Details

Journal
Neuropsychological Rehabilitation
Published
2026-02-11
DOI
https://doi.org/10.1080/09602011.2026.2623949
Primary Topic
Traumatic Brain Injury Research
Type
article
Field-Weighted Citation Impact
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article

A blended digital therapy for depression in people with acquired brain injury: A feasibility and acceptability study

Grace Lakey, Rutendo Kusosa, Matteo Cella, Erin Dawe-Lane et al.
Neuropsychological Rehabilitation
Traumatic Brain Injury Research
article

A blended digital therapy for depression in people with acquired brain injury: A feasibility and acceptability study

Grace Lakey, Rutendo Kusosa, Matteo Cella, Erin Dawe-Lane, Jaqueline Edwards, Sara Simblett
article en

Abstract

Depression following Acquired Brain Injury (ABI) is common, persistent and debilitating, yet access to psychological treatment is limited. Digital therapies, provided alongside clinician support, may help overcome these barriers. This study evaluated the feasibility, acceptability, and potential benefits of a blended intervention for depression post-ABI, using a mixed-method approach. Individuals with ABI and depression were offered a 4-week intervention (<i>MyACTION</i>), delivered via a novel smartphone app, alongside weekly video therapy sessions. Measures of depression, anxiety, and self-efficacy were collected pre- and post-intervention. Feasibility was evaluated through recruitment, retention, engagement, and usability ratings. Acceptability was assessed via post-treatment interviews. Initial indication of benefit was evaluated through change in scores in outcome measures. Twenty-one individuals consented, 19 completed the intervention, and 18 completed post-intervention interviews. On average, 82% of daily app tasks were completed. Overall, the app received "good" usability ratings. Barriers and facilitators to engagement were (1) health status, (2) motivation, (3) perceived utility, (4) usability, (5) accessibility, and (6) timing. Reductions in depression and anxiety were observed post-intervention. <i>MyACTION</i> was feasible and acceptable for individuals with ABI and depression. High engagement and positive feedback suggest blended digital approaches may help increase access to psychological support in this population.

Neuropsychological Rehabilitation
King's College London (GB), South London and Maudsley NHS Foundation Trust (GB), University College London (GB)
Openalex Percentile: Top 57%
Traumatic Brain Injury Research
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A blended digital therapy for depression in people with acquired brain injury: A feasibility and acceptability study — Grace Lakey, Rutendo Kusosa, et al. · Neuropsychological Rehabilitation (2026) | TGRS Research Map | TGRS