Systematized Linear Porokeratosis With Palmoplantar and Nail Involvement: A Rare Presentation

Porokeratosis encompasses a group of genetically and clinically heterogenous dermatoses characterized by abnormal epidermal keratinization, with the cornoid lamella being the hallmark histological feature. Linear porokeratosis, a rare variant of porokeratosis, typically manifests early in life, with lesions that follow the lines of Blaschko and carry the highest risk of malignancy transformation. Here, we present a case of systematized linear porokeratosis in a 48-year-old male with childhood onset, notable for the rare co-existence of palmoplantar and nail involvement. This report emphasizes the importance of long-term surveillance in patients with linear porokeratosis due to its malignant potential.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2026-02-12
DOI
https://doi.org/10.7759/cureus.103504
Primary Topic
Genetic and rare skin diseases.
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Systematized Linear Porokeratosis With Palmoplantar and Nail Involvement: A Rare Presentation

Adikrishnan Swaminathan, Divya Raviprakash, Greeshma Peddireddy, Leena Dennis Joseph
Cureus
Genetic and rare skin diseases.
article

Systematized Linear Porokeratosis With Palmoplantar and Nail Involvement: A Rare Presentation

Adikrishnan Swaminathan, Divya Raviprakash, Greeshma Peddireddy, Leena Dennis Joseph
article en

Abstract

Porokeratosis encompasses a group of genetically and clinically heterogenous dermatoses characterized by abnormal epidermal keratinization, with the cornoid lamella being the hallmark histological feature. Linear porokeratosis, a rare variant of porokeratosis, typically manifests early in life, with lesions that follow the lines of Blaschko and carry the highest risk of malignancy transformation. Here, we present a case of systematized linear porokeratosis in a 48-year-old male with childhood onset, notable for the rare co-existence of palmoplantar and nail involvement. This report emphasizes the importance of long-term surveillance in patients with linear porokeratosis due to its malignant potential.

CureusVol. 18(2)
Sri Ramachandra Institute of Higher Education and Research (IN)
Good health and well-being
Openalex Percentile: Top 56%
Genetic and rare skin diseases.
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.