Skeletal muscle health in childhood cancer survivors: a systematic review and meta-analysis

Childhood cancer survivors exhibit significant deficits in muscle quantity and function. Future research should focus on developing international consensus guidelines for standardized, clinically meaningful assessments that include lower-body function and muscle quantity. Additionally, investigating muscle quality may lead to a better understanding of the mechanisms underlying these deficits and help inform targeted interventions aimed at preserving long-term health in CCS.

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Publication Details

Journal
Supportive Care in Cancer
Published
2026-02-13
DOI
https://doi.org/10.1007/s00520-026-10425-3
Primary Topic
Childhood Cancer Survivors' Quality of Life
Type
article
Field-Weighted Citation Impact
0.00
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Skeletal muscle health in childhood cancer survivors: a systematic review and meta-analysis

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Skeletal muscle health in childhood cancer survivors: a systematic review and meta-analysis

Mayank Dhamija, Francesco Bettariga, Santosh Valvi, Daniel A. Galvão, Dennis R. Taaffe, Anna Maria Markarian, Dr Jodie Cochrane Wilkie, Kerrie Graham, Carolyn J. Peddle-McIntyre, Robert U. Newton, Nicholas G. Gottardo, Catriona M. Buchanan
article en

Abstract

Childhood cancer survivors exhibit significant deficits in muscle quantity and function. Future research should focus on developing international consensus guidelines for standardized, clinically meaningful assessments that include lower-body function and muscle quantity. Additionally, investigating muscle quality may lead to a better understanding of the mechanisms underlying these deficits and help inform targeted interventions aimed at preserving long-term health in CCS.

Supportive Care in CancerVol. 34(3)
Edith Cowan University (AU), The University of Queensland (AU), The Kids Research Institute Australia (AU), The University of Western Australia (AU), Princess Margaret Hospital for Children (AU), Western Australian Museum (AU), MicroGen Biotech (Ireland) (IE), Perth Children's Hospital, Southern Cross University (AU), The University of Notre Dame Australia (AU)
Good health and well-being
Openalex Percentile: Top 57%
Childhood Cancer Survivors' Quality of Life
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