The diagnostic and immunomodulatory role of IL-37 in pediatric sepsis

This study identifies elevated IL-37 as a potential diagnostic biomarker for pediatric sepsis and demonstrates its role in modulating hyperinflammation and immune cell differentiation. IL-37 represents a promising therapeutic target for pediatric sepsis.

Authors

Institutions

Publication Details

Journal
Frontiers in Immunology
Published
2026-02-12
DOI
https://doi.org/10.3389/fimmu.2026.1765956
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The diagnostic and immunomodulatory role of IL-37 in pediatric sepsis

FangYi Huang, Changrui Sun, Chunxiang Wu, Zhixin Song et al.
Frontiers in Immunology
Psoriasis: Treatment and Pathogenesis
article

The diagnostic and immunomodulatory role of IL-37 in pediatric sepsis

FangYi Huang, Changrui Sun, Chunxiang Wu, Zhixin Song, Yanling Zhang, Hao Yang, Jin Ma
article en

Abstract

This study identifies elevated IL-37 as a potential diagnostic biomarker for pediatric sepsis and demonstrates its role in modulating hyperinflammation and immune cell differentiation. IL-37 represents a promising therapeutic target for pediatric sepsis.

Frontiers in ImmunologyVol. 17
University of Electronic Science and Technology of China (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 56%
Psoriasis: Treatment and Pathogenesis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.