Association of CT-assessed sarcopenia and the development of immune-related adverse events and overall survival: a multistate survival analysis
In this NSCLC cohort, CT-assessed sarcopenia was not associated with direct mortality without irAEs but was linked to a lower likelihood of developing irAEs and reduced mortality after severe irAEs. These findings suggest that body composition may have prognostic value and influence responses to immunotherapy.
Authors
- Erick Suazo-Zepeda (ORCID: https://orcid.org/0000-0003-1518-7405)
- Marjolein A. Heuvelmans (ORCID: https://orcid.org/0000-0002-5712-4085)
- Alain R. Viddeleer
- Geertruida H. de Bock (ORCID: https://orcid.org/0000-0003-3104-4471)
- T. Jeroen N. Hiltermann
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Translational Lung Cancer Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.21037/tlcr-2025-aw-1140
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00