Mechanisms of Gualou Beimu Yin in suppressing the development and metastasis of triple-negative breast cancer: an integrated study based on network pharmacology, transcriptomics, and metabolomics.
We confirmed that GLBMY inhibits the development and metastasis of TNBC through the MAPK/Erk and IL6-STAT signalling pathways. GLBMY shows promise as a long-term supplementary or alternative therapy for TNBC, offering new insights for TNBC treatment.
Authors
- Wenyuan Gao
- Xiongzhi WU
- Haoran ZHANG
- Shuang LIU
- Ao JIA
Institutions
- Tianjin University of Science and Technology (CN)
- Tianjin Nankai Hospital (CN)
- Tianjin Institute of Pharmaceutical Research (China) (CN)
Publication Details
- Journal
- PubMed
- Published
- 2026-02-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.2026.01.014
- Primary Topic
- Bioactive natural compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00