Staging Laparoscopy After Neoadjuvant Treatment for Pancreatic Cancer to Prevent Non-Therapeutic Laparotomy

A SL just prior to surgical exploration in patients with PDAC following neoadjuvant treatment was able to detect occult metastases with a NNT of 8. Tailored use of SL only in patients with one or two risk factors would further lower this NNT.

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Publication Details

Journal
Annals of Surgery
Published
2026-02-12
DOI
https://doi.org/10.1097/sla.0000000000007025
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
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article

Staging Laparoscopy After Neoadjuvant Treatment for Pancreatic Cancer to Prevent Non-Therapeutic Laparotomy

C. Yung Nio, Esther N. Dekker, Marcel G.W. Dijkgraaf, Mike S L Liem et al.
Annals of Surgery
Pancreatic and Hepatic Oncology Research
article

Staging Laparoscopy After Neoadjuvant Treatment for Pancreatic Cancer to Prevent Non-Therapeutic Laparotomy

C. Yung Nio, Esther N. Dekker, Marcel G.W. Dijkgraaf, Mike S L Liem, Marjolein Y.V. Homs, Jacob L. van Dam, Quisette P. Janssen, Gijs A Patijn, Bas Groot Koerkamp, Ignace H. de Hingh, Olivier R. Busch, Ronald M. van Dam, B. Marion van der Kolk, Hjalmar C. van Santvoort, Johanna W. Wilmink, Marc G. Besselink, Casper H.J. van Eijck, for the Dutch Pancreatic Cancer Group, Sebastiaan Festen, Geertjan van Tienhoven, Ingmar F. Rompen, Thomas F. Stoop, Erwin van der Harst
article en

Abstract

A SL just prior to surgical exploration in patients with PDAC following neoadjuvant treatment was able to detect occult metastases with a NNT of 8. Tailored use of SL only in patients with one or two risk factors would further lower this NNT.

Annals of Surgery
Radboud University Nijmegen (NL), Leiden University Medical Center (NL), Catharina Ziekenhuis (NL), Medisch Spectrum Twente (NL), University Medical Center (US), Radboud University Medical Center (NL), University Medical Center Utrecht (NL), Maastricht University (NL), OLVG (NL), Amphia Ziekenhuis (NL), Amsterdam Neuroscience (NL), Maasstad Ziekenhuis (NL), Isala (NL), Erasmus MC Cancer Institute (NL), Amsterdam University Medical Centers (NL), University of Colorado Anschutz Medical Campus (US), Amsterdam University of Applied Sciences (NL), University of Amsterdam (NL)
Good health and well-being
Openalex Percentile: Top 58%
Pancreatic and Hepatic Oncology Research
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