Development and validation of a gemcitabine sensitivity-related long noncoding RNA signature for predicting the prognosis and subtypes of bladder cancer

We identified critical prognostic associations between GSRlncRNAs and BLCA. Based on these findings, we constructed a GSRlncRNA-based predictive signature, which demonstrated considerable potential for risk stratification and personalized treatment decisions. Functional experiments further validated the involvement of GSRlncRNAs in BLCA progression.

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Publication Details

Journal
Translational Andrology and Urology
Published
2026-02-01
DOI
https://doi.org/10.21037/tau-2025-1-970
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00
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article

Development and validation of a gemcitabine sensitivity-related long noncoding RNA signature for predicting the prognosis and subtypes of bladder cancer

Xingxing Tang, Peng Du, Xiao Yang, Yushuang Cui et al.
Translational Andrology and Urology
Cancer-related molecular mechanisms research
article

Development and validation of a gemcitabine sensitivity-related long noncoding RNA signature for predicting the prognosis and subtypes of bladder cancer

Xingxing Tang, Peng Du, Xiao Yang, Yushuang Cui, Yong Yang, Jia Liu
article en

Abstract

We identified critical prognostic associations between GSRlncRNAs and BLCA. Based on these findings, we constructed a GSRlncRNA-based predictive signature, which demonstrated considerable potential for risk stratification and personalized treatment decisions. Functional experiments further validated the involvement of GSRlncRNAs in BLCA progression.

Translational Andrology and UrologyVol. 15(2)
Peking University (CN), Peking University Cancer Hospital (CN)
Good health and well-being
Openalex Percentile: Top 60%
Cancer-related molecular mechanisms research
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