Dietary glycemic index, glycemic load, carbohydrate quality index, and low-carbohydrate diet score and their association with sperm DNA damage in unexplained male infertility

Higher dietary carbohydrate quality and adherence to a lower carbohydrate dietary pattern showed an inverse association with sperm DNA damage in men with unexplained infertility. These findings suggest a potential link between carbohydrate-related dietary patterns and sperm genomic integrity, but causal relationships cannot be inferred from this observational study.

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Publication Details

Journal
Genes & Nutrition
Published
2026-02-12
DOI
https://doi.org/10.1186/s12263-026-00795-y
Primary Topic
Sperm and Testicular Function
Type
article
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article

Dietary glycemic index, glycemic load, carbohydrate quality index, and low-carbohydrate diet score and their association with sperm DNA damage in unexplained male infertility

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Dietary glycemic index, glycemic load, carbohydrate quality index, and low-carbohydrate diet score and their association with sperm DNA damage in unexplained male infertility

Naser Amirjannati, Seyed Ali Keshavarz, Negin Amirjannati, Ghazaleh Eslamian, Maryam Mehrkia, Mehran Nouri
article en

Abstract

Higher dietary carbohydrate quality and adherence to a lower carbohydrate dietary pattern showed an inverse association with sperm DNA damage in men with unexplained infertility. These findings suggest a potential link between carbohydrate-related dietary patterns and sperm genomic integrity, but causal relationships cannot be inferred from this observational study.

Genes & NutritionVol. 21(1)
Islamic Azad University, Science and Research Branch (IR), Yahoo (Spain) (ES), Biotechnology Research Center (IR), National Nutrition and Food Technology Research Institute (IR), Babol University of Medical Sciences (IR)
Zero hunger
Openalex Percentile: Top 60%
Sperm and Testicular Function
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