The effect of perioperative dexmedetomidine on early extubation time in patients undergoing pediatric cardiac surgical patients: A retrospective cohort study

Perioperative dexmedetomidine was paradoxically associated with prolonged mechanical ventilation and increased postoperative respiratory support requirements. These findings suggest that dexmedetomidine should be employed as an adjunct rather than a substitute for opioids, particularly in patients undergoing complex procedures. Prospective randomized trials are warranted to refine dexmedetomidine's role in fast-track extubation protocols in this high-risk population.

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Publication Details

Journal
Turkish Journal of Thoracic and Cardiovascular Surgery
Published
2026-02-12
DOI
https://doi.org/10.4274/tjtcs.2025.28329
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00
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article

The effect of perioperative dexmedetomidine on early extubation time in patients undergoing pediatric cardiac surgical patients: A retrospective cohort study

Ayşe Duygu Kavas, Ayten Saraçoğlu, Şenay Göksu, Tolga Saracoglu et al.
Turkish Journal of Thoracic and Cardiovascular Surgery
Anesthesia and Sedative Agents
article

The effect of perioperative dexmedetomidine on early extubation time in patients undergoing pediatric cardiac surgical patients: A retrospective cohort study

Ayşe Duygu Kavas, Ayten Saraçoğlu, Şenay Göksu, Tolga Saracoglu, Zeliha Alıcıkuş, Ceren Atatepe
article en

Abstract

Perioperative dexmedetomidine was paradoxically associated with prolonged mechanical ventilation and increased postoperative respiratory support requirements. These findings suggest that dexmedetomidine should be employed as an adjunct rather than a substitute for opioids, particularly in patients undergoing complex procedures. Prospective randomized trials are warranted to refine dexmedetomidine's role in fast-track extubation protocols in this high-risk population.

Turkish Journal of Thoracic and Cardiovascular Surgery
University of North Florida (US), University of Florida Health (US), Ümraniye Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), Türk Anesteziyoloji ve Reanimasyon Derneği (TR), University of Florida Health Science Center (US)
Good health and well-being
Openalex Percentile: Top 56%
Anesthesia and Sedative Agents
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