Association between nucleic acid COVID-19 vaccines and acute myocardial infarction in adults: a systematic review

High-quality population-based evidence from 14 independent cohorts does not support a causal association between nucleic acid-based COVID-19 vaccines and AMI. Case reports lack the methodological rigor to establish causality. The documented protective effects after booster doses and consistency across diverse populations demonstrate vaccine cardiovascular safety, supporting continued vaccination policies.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-02-12
DOI
https://doi.org/10.3389/fcvm.2026.1752169
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between nucleic acid COVID-19 vaccines and acute myocardial infarction in adults: a systematic review

Carlos Alberto Matias‐Cervantes, Juan Alpuche, Miguel Angel Mayoral-Chávez, Dalia I. Castellanos-Hernández
Frontiers in Cardiovascular Medicine
SARS-CoV-2 and COVID-19 Research
article

Association between nucleic acid COVID-19 vaccines and acute myocardial infarction in adults: a systematic review

Carlos Alberto Matias‐Cervantes, Juan Alpuche, Miguel Angel Mayoral-Chávez, Dalia I. Castellanos-Hernández
article en

Abstract

High-quality population-based evidence from 14 independent cohorts does not support a causal association between nucleic acid-based COVID-19 vaccines and AMI. Case reports lack the methodological rigor to establish causality. The documented protective effects after booster doses and consistency across diverse populations demonstrate vaccine cardiovascular safety, supporting continued vaccination policies.

Frontiers in Cardiovascular MedicineVol. 13
Benito Juárez Autonomous University of Oaxaca (MX)
Good health and well-being
Openalex Percentile: Top 57%
SARS-CoV-2 and COVID-19 Research
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