Relationship between plasma concentrations of ustekinumab at week 8 and its effectiveness in patients with Crohn's disease
This study confirms the association between ustekinumab concentrations at week 8 and treatment effectiveness in Crohn's disease. A concentration >13.29 μg/mL at week 8 was identified as a predictive marker of biochemical remission at week 24, which could serve as a basis for future therapeutic decision-making algorithms.
Authors
- Laura Ramos
- Ana Salas Pérez
- Betel Del Rosario García (ORCID: https://orcid.org/0000-0002-7786-980X)
- Sergio Medina Chico
- Ruth Ramos Díaz
- Fernando Gutiérrez Nicolás
- Cristina Reygosa Castro
- Inmaculada Alonso Abreu
- Marta Carrillo Palau
Institutions
- Hospital Universitario de Canarias (ES)
- Fundación Canaria de Investigación Sanitaria (ES)
Publication Details
- Journal
- Farmacia Hospitalaria
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.farma.2026.01.002
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00