Patterns and Clinical Outcomes of Physical Activity and Sedentary Behavior Across 20 Million Days of Wearable Monitoring in U.S. Adults
In this nationwide cohort of U.S. adults, wearable-derived physical activity and sedentary behavior showed distinct temporal and geographic patterns with significant disease-specific associations with clinical outcomes. These findings support the use of longitudinal high-resolution wearable data for advancing personalized guidelines of physical activity and sedentary behavior.
Authors
- Arash Aghajani Nargesi (ORCID: https://orcid.org/0000-0002-6182-5271)
- Tal Shnitzer (ORCID: https://orcid.org/0000-0001-9058-1870)
- Sam Friedman (ORCID: https://orcid.org/0000-0002-0688-2169)
- Romuladus E. Azuine
- Mahnaz Maddah (ORCID: https://orcid.org/0000-0002-9837-6000)
- Patrick T. Ellinor
- R. Lupi
- Nakia Mack
- Andri Kadaifciu
- V Dsouza
- S Jurgens
- Christopher D. Anderson
- Geoffrey S. Ginsburg
- Chris Lunt
Institutions
- Broad Institute (US)
- Political Research Associates (US)
- Brigham and Women's Hospital (US)
- National Institutes of Health (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-02-12
- DOI
- https://doi.org/10.64898/2026.02.11.26346079
- Primary Topic
- Physical Activity and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- Bayer
- Novo Nordisk
- National Institutes of Health
- National Heart, Lung, and Blood Institute