Therapeutic potential of pharmacological components of Salvia miltiorrhiza against atherosclerosis: A preclinical systematic review and meta-analysis
The pharmacological components of Salvia miltiorrhiza attenuate AS by regulating lipid metabolism, anti-inflammatory and antioxidant actions, improving endothelial function, modulating of vascular smooth muscle cells, remodeling extracellular matrix, and regulating programmed cell death. These findings provide translational insights that pave the way for subsequent preclinical and early-clinical studies, pending systematic validation through more rigorous research.
Authors
- Mengwen Huang
- Wenjie Liu (ORCID: https://orcid.org/0000-0002-4907-2465)
- Ziyi Sun (ORCID: https://orcid.org/0009-0004-8391-8323)
- Xiaoning Sun
- Jin Zhang
- Qingqing Wang
- Lingyan Jiang
- Kuiwu Yao
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.1016/j.jep.2026.121294
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00