Posterior cingulate GABA levels are associated with depression severity during the premenstrual phase in women
These findings suggest that PCC_GABA concentrations are associated with depressive symptom severity in unmedicated women during the premenstrual phase of the menstrual cycle. Further research is warranted to elucidate the neurosteroid-mediated modulation of GABAergic neurotransmission in the pathophysiology of mood disorders.
Authors
- Raul Osorio-Duran
- Mónica Flores-Ramos
- Richard Edden
- Estefanía Magaña Saavedra
Institutions
- Johns Hopkins University (US)
- Vietnam National Children's Hospital (VN)
- Universidad del Valle de México (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1016/j.jad.2026.121396
- Primary Topic
- Menstrual Health and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00