<scp>A</scp> Role for Non‐Canonical Caspases in Fungal Allergic Airway Disease
Summary Inhibition of the murine ortholog caspase‐11 reduces neutrophilia and inflammatory cytokine levels. Wedelolactone or its derivatives offer a potential therapeutic approach for mixed or steroid‐resistant inflammation in allergic fungal airway disease.
Authors
- I. Addcock
- Thomas J Williams (ORCID: https://orcid.org/0000-0002-1201-2944)
- Darius Armstrong‐James
- Luis E. Gonzales‐Huerta
- U‐BIORPED Study Group
- Kian Fan Chung
- Anand Shah
- Nazanin Zounemat Kermani
Institutions
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Royal Brompton & Harefield NHS Foundation Trust (GB)
- Harefield Hospital (GB)
- NIHR Imperial Biomedical Research Centre (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1111/cea.70237
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cystic Fibrosis Trust