Evaluating the Impact of Blood Brain Barrier-Penetrant ACE Inhibitors on HIV-Associated Neurocognitive Disorders
BBB-penetrant ACEi were associated with a reduced risk of incident HAND in a propensity score-matched cohort of PWH. These findings support further investigation into repurposing centrally acting ACEi as a potential neuroprotective strategy in the HIV population.
Authors
- Tammy H. Cummings (ORCID: https://orcid.org/0000-0001-7978-7157)
- Michael Shtutman (ORCID: https://orcid.org/0000-0002-2458-3226)
- Joseph Magagnoli (ORCID: https://orcid.org/0000-0002-8568-0097)
- Michael D. Wyatt (ORCID: https://orcid.org/0000-0003-1815-9565)
- Ilya Tyagin (ORCID: https://orcid.org/0000-0002-0249-1072)
- Ilya Safro
- Sasha Sikirzhytskaya
- S. Scott Sutton
Institutions
- University of South Carolina (US)
- Dorn Research Institute (US)
- University of Delaware (US)
Publication Details
- Journal
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1097/qai.0000000000003847
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00