Modified X‐ray tube for high dose rate FLASH radiotherapy research

Modifying the housing of rotating anode X-ray tubes enhances the efficient delivery of ultra-high dose rate radiation by shortening the SSD and expanding the beam exit port. Although the use of tubes for FLASH experiments will have problems such as uneven dose depth and shortened tube life, this improved tube configuration enables high-dose-rate irradiation, providing an accessible platform for laboratory-based FLASH studies.

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Publication Details

Journal
Medical Physics
Published
2026-02-01
DOI
https://doi.org/10.1002/mp.70341
Primary Topic
Radiation Therapy and Dosimetry
Type
article
Field-Weighted Citation Impact
0.00

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article

Modified X‐ray tube for high dose rate FLASH radiotherapy research

Xu Cao, Jiaxu Guo, Qi Pan, Brian W. Pogue et al.
Medical Physics
Radiation Therapy and Dosimetry
article

Modified X‐ray tube for high dose rate FLASH radiotherapy research

Xu Cao, Jiaxu Guo, Qi Pan, Brian W. Pogue, Yue Wang, Qingchao Ma, Shouping Zhu, Wenhua Zhan, Ke Li, Yonghua Zhan, Liwen Cui, Yi Lu
article en

Abstract

Modifying the housing of rotating anode X-ray tubes enhances the efficient delivery of ultra-high dose rate radiation by shortening the SSD and expanding the beam exit port. Although the use of tubes for FLASH experiments will have problems such as uneven dose depth and shortened tube life, this improved tube configuration enables high-dose-rate irradiation, providing an accessible platform for laboratory-based FLASH studies.

Medical PhysicsVol. 53(2)
Dartmouth College (US), Xidian University (CN), Capital Medical University (CN), Xi'an Medical University (CN), Ningxia Medical University (CN), Ningxia Medical University General Hospital (CN)
National Natural Science Foundation of China, China Postdoctoral Science Foundation, Beijing Postdoctoral Science Foundation, Natural Science Foundation of Chongqing, Centre Scientifique et Technique du Bâtiment, National Institutes of Health
Openalex Percentile: Top 61%
Radiation Therapy and Dosimetry
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