Association Between Intraoperative Hyperlactatemia and Infection After Cardiac Surgery With Cardiopulmonary Bypass: A Multicenter Retrospective Study
Consistent with our hypothesis, intraoperative hyperlactatemia was independently associated with a 1.49-fold increased risk of postoperative infection in CPB-assisted cardiac surgery. Notably, maintaining intraoperative blood lactate levels below 2.7 mmol/L might lower the risk of such infections.
Authors
- Yewei Shi
- Chao Chen (ORCID: https://orcid.org/0000-0002-5114-2282)
- Jun Lü (ORCID: https://orcid.org/0000-0003-4121-7815)
- Zhenyan Zhu
- Xinglong Xiong
- Jielei Pan
- Dongxu Chen
- Yusu Wang
- Jing Shi
Institutions
- Guiyang Medical University (CN)
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
Publication Details
- Journal
- World Journal of Surgery
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1002/wjs.70265
- Primary Topic
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sichuan University
- Guizhou Medical University
- West China Hospital, Sichuan University
- Science and Technology Program of Guizhou Province