Synthesis of Various Heterocyclic and Carbocyclic Compounds From 3‐(2‐Formylcycloalkenyl)‐Acrylicester (FCAE)
ABSTRACT 3‐(2‐formylcycloalkenyl)‐acrylic ester (FCAE) acts as an important building block in synthetic organic chemistry. Co‐existence of α, β‐unsaturated ester and α, β‐unsaturated aldehyde makes it a useful scaffold for the synthesis of diverse carbocyclic and heterocyclic compounds through Michael addition, condensation reaction, coupling reaction, multicomponent reaction, cascade cyclization, functional group conversion, and asymmetric synthesis. The literature covers the area since last couple of decades. In this review, we outline the various pathways for bicyclic, tricyclic, tetracyclic, pentacyclic, and polycyclic heterocyclic scaffolds with their mechanistic details.
Authors
- Susanta Kumar Manna (ORCID: https://orcid.org/0000-0001-8435-3003)
- Biswajit Ghosh (ORCID: https://orcid.org/0000-0003-1360-8202)
- Rabindra Nath Sana
- Sampa Mondal
- Soumen Giri
- Bidhusree Maity
Institutions
- Saha Institute of Nuclear Physics (IN)
- Jadavpur University (IN)
- KIIT University (IN)
- Indian Institute of Engineering Science and Technology, Shibpur (IN)
Publication Details
- Journal
- ChemistrySelect
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/slct.202505976
- Primary Topic
- Synthesis of heterocyclic compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00