USEtox modeling of children’s exposures to Bisphenol A (BPA) and alternatives in toys
This study offers insights into children's exposure to BPA and its alternatives in toys, filling in the knowledge gaps on exposures to these chemicals. USEtox modeling identifies dominant exposure pathways and evaluates aggregate exposure from the use of different toy types, demonstrating the ability of USEtox to quantify exposures to both well-known chemicals as well as new alternatives. The research underscores the variability in exposure doses based on toy material, chemical properties, and children's behavior, providing valuable science-based and quantified data to guide safer product design. Policymakers can leverage these findings to prioritize products for regulation and protect public health.
Authors
- Lynn Nakayama Wong
- Thomas E. McKone (ORCID: https://orcid.org/0000-0001-8931-1443)
- Michelle Romero-Franco
- Xiaoying Zhou (ORCID: https://orcid.org/0000-0002-7901-2842)
- Olivier Jolliet (ORCID: https://orcid.org/0000-0001-6955-4210)
- Qingyu Meng (ORCID: https://orcid.org/0009-0003-1962-2395)
- Hyeong-Moo Shin
- Nathalie Pham
- Lei Huang
Institutions
- California Department of Toxic Substances Control (US)
- Baylor University (US)
- University of Michigan (US)
- University of California, Berkeley (US)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Journal of Exposure Science & Environmental Epidemiology
- Published
- 2026-02-12
- DOI
- https://doi.org/10.1038/s41370-025-00827-6
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Toxic Substances Control
- Novo Nordisk
- Danmarks Tekniske Universitet
- Novo Nordisk Fonden