Biochemical and cellular effects of squalene on human gingival fibroblasts in an in vitro wound healing model

Considering its non-cytotoxic profile on HGF and its effects on TGF-β, type-I, and type-III collagen expression, squalene appears to facilitate wound healing by promoting wound closure.

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Publication Details

Journal
BMC Complementary Medicine and Therapies
Published
2026-02-12
DOI
https://doi.org/10.1186/s12906-026-05298-2
Primary Topic
Wound Healing and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Biochemical and cellular effects of squalene on human gingival fibroblasts in an in vitro wound healing model

Ayşe Mine Yılmaz, Hafize Öztürk Özener, Akın Özdemir
BMC Complementary Medicine and Therapies
Wound Healing and Treatments
article

Biochemical and cellular effects of squalene on human gingival fibroblasts in an in vitro wound healing model

Ayşe Mine Yılmaz, Hafize Öztürk Özener, Akın Özdemir
article en

Abstract

Considering its non-cytotoxic profile on HGF and its effects on TGF-β, type-I, and type-III collagen expression, squalene appears to facilitate wound healing by promoting wound closure.

BMC Complementary Medicine and TherapiesVol. 26(1)
Maltepe University (TR), Marmara University (TR)
Good health and well-being
Openalex Percentile: Top 57%
Wound Healing and Treatments
DOIOpen Access PDFOpenAlex
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Biochemical and cellular effects of squalene on human gingival fibroblasts in an in vitro wound healing model — Ayşe Mine Yılmaz, Hafize Öztürk Özener, et al. · BMC Complementary Medicine and Therapies (2026) | TGRS Research Map | TGRS