Diagnostic Value of the Systemic Immune-Inflammation Index in Differentiating Acute Appendicitis From Familial Mediterranean Fever in Children

The systemic immune-inflammation index is significantly elevated in pediatric patients with acute appendicitis compared with those experiencing Familial Mediterranean Fever attacks and shows good diagnostic performance in this differential setting. The combined use of hematological indices may further enhance diagnostic discrimination and serve as a supportive tool in the evaluation of children presenting with acute abdominal pain.

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Publication Details

Journal
Pediatric Emergency Care
Published
2026-02-13
DOI
https://doi.org/10.1097/pec.0000000000003582
Primary Topic
Appendicitis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic Value of the Systemic Immune-Inflammation Index in Differentiating Acute Appendicitis From Familial Mediterranean Fever in Children

Ceyhan Şahin, Neslihan Gülçin, T. Tekin, Eray Tunce et al.
Pediatric Emergency Care
Appendicitis Diagnosis and Management
article

Diagnostic Value of the Systemic Immune-Inflammation Index in Differentiating Acute Appendicitis From Familial Mediterranean Fever in Children

Ceyhan Şahin, Neslihan Gülçin, T. Tekin, Eray Tunce, AYTEKİN KAYMAKÇI, Cengiz Gul, B Sözeri, Mehmet Arpacik, Semih Lütfi Mirapoğlu
article en

Abstract

The systemic immune-inflammation index is significantly elevated in pediatric patients with acute appendicitis compared with those experiencing Familial Mediterranean Fever attacks and shows good diagnostic performance in this differential setting. The combined use of hematological indices may further enhance diagnostic discrimination and serve as a supportive tool in the evaluation of children presenting with acute abdominal pain.

Pediatric Emergency Care
Pediatric Oncology Group (CA), Ümraniye Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR)
Reduced inequalities
Openalex Percentile: Top 60%
Appendicitis Diagnosis and Management
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Diagnostic Value of the Systemic Immune-Inflammation Index in Differentiating Acute Appendicitis From Familial Mediterranean Fever in Children — Ceyhan Şahin, Neslihan Gülçin, et al. · Pediatric Emergency Care (2026) | TGRS Research Map | TGRS