Comparing <scp>SGLT2i</scp> and Other Oral Antidiabetic Drugs as Dual Therapy Add‐On to Metformin in Type 2 Diabetes: A Systematic Review and Meta‐Analysis

Compared with other ODTs, SGLT-2i plus metformin exhibited overall comparable efficacy and safety, with a lower risk of hypoglycaemia and greater weight reduction at Week 52.

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Publication Details

Journal
Endocrinology Diabetes & Metabolism
Published
2026-02-12
DOI
https://doi.org/10.1002/edm2.70176
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparing SGLT2i and Other Oral Antidiabetic Drugs as Dual Therapy Add‐On to Metformin in Type 2 Diabetes: A Systematic Review and Meta‐Analysis

Yuhang Ma, YONGDE PENG, Yi Lin, Xiaoying Ding
Endocrinology Diabetes & Metabolism
Diabetes Treatment and Management
article

Comparing SGLT2i and Other Oral Antidiabetic Drugs as Dual Therapy Add‐On to Metformin in Type 2 Diabetes: A Systematic Review and Meta‐Analysis

Yuhang Ma, YONGDE PENG, Yi Lin, Xiaoying Ding
article en

Abstract

Compared with other ODTs, SGLT-2i plus metformin exhibited overall comparable efficacy and safety, with a lower risk of hypoglycaemia and greater weight reduction at Week 52.

Endocrinology Diabetes & MetabolismVol. 9(2)
Shanghai Jiao Tong University (CN)
AstraZeneca
Good health and well-being
Openalex Percentile: Top 60%
Diabetes Treatment and Management
DOIOpen Access PDFOpenAlex
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Comparing <scp>SGLT2i</scp> and Other Oral Antidiabetic Drugs as Dual Therapy Add‐On to Metformin in Type 2 Diabetes: A Systematic Review and Meta‐Analysis — Yuhang Ma, YONGDE PENG, et al. · Endocrinology Diabetes & Metabolism (2026) | TGRS Research Map | TGRS