Potentially Clinically Significant Drug-Drug Interactions in Older Adults with Atrial Fibrillation and Multimorbidity: Prevalence, Correlates, and Association with Adverse Clinical Outcomes in a Swedish National Register-Based Study

Potentially clinically significant DDIs were prevalent in older adults with AF and multimorbidity, with adverse clinical implications. Identifying these high-risk groups is essential for preventive strategies and effective clinical management.

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Publication Details

Journal
Cardiovascular Drugs and Therapy
Published
2026-02-12
DOI
https://doi.org/10.1007/s10557-025-07825-8
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Potentially Clinically Significant Drug-Drug Interactions in Older Adults with Atrial Fibrillation and Multimorbidity: Prevalence, Correlates, and Association with Adverse Clinical Outcomes in a Swedish National Register-Based Study

Cheïma Amrouch, Jonas W. Wastesson, Antoneta Granic, Ine Simal et al.
Cardiovascular Drugs and Therapy
Atrial Fibrillation Management and Outcomes
article

Potentially Clinically Significant Drug-Drug Interactions in Older Adults with Atrial Fibrillation and Multimorbidity: Prevalence, Correlates, and Association with Adverse Clinical Outcomes in a Swedish National Register-Based Study

Cheïma Amrouch, Jonas W. Wastesson, Antoneta Granic, Ine Simal, Amaia Calderón-Larrañaga, Astrid D. H. Brys, Gregory Y. H. Lip, Cecilia Damiano, Davide Liborio Vetrano, Mirko Petrovic, Dirk De Bacquer, Delphine De Smedt, Søren P. Johnsen, Lu Dai, Nicola Ferri
article en

Abstract

Potentially clinically significant DDIs were prevalent in older adults with AF and multimorbidity, with adverse clinical implications. Identifying these high-risk groups is essential for preventive strategies and effective clinical management.

Cardiovascular Drugs and Therapy
University of Padua (IT), University of Liverpool (GB), Stockholm University (SE), Istituto Superiore di Sanità (IT), Swedish Institute of International Affairs (SE), Ghent University Hospital (BE), Karolinska Institutet (SE), Ghent University (BE), Liverpool Heart and Chest Hospital (GB), Stockholm Gerontology Research Center Foundation (SE), Liverpool John Moores University (GB), Aalborg University (DK)
European Commission
Good health and well-being
Openalex Percentile: Top 61%
Atrial Fibrillation Management and Outcomes
DOIOpen Access PDFOpenAlex
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Potentially Clinically Significant Drug-Drug Interactions in Older Adults with Atrial Fibrillation and Multimorbidity: Prevalence, Correlates, and Association with Adverse Clinical Outcomes in a Swedish National Register-Based Study — Cheïma Amrouch, Jonas W. Wastesson, et al. · Cardiovascular Drugs and Therapy (2026) | TGRS Research Map | TGRS