Application of Shengxuening tablets for the prevention of anemia in pregnancy: stratified efficacy analysis based on serum ferritin levels and thalassemia subgroups

SXN tablets effectively ameliorate ID and anemia in both the general obstetric population and pregnant women with the thalassemia trait. The greatest benefit occurs when prophylaxis is initiated at baseline SF ≥30 μg/L. Baseline SF levels positively correlate with therapeutic response, indicating that adequate iron reserves enhance treatment efficacy. Routine, guideline-based iron supplementation should remain a cornerstone of antenatal care; however, individualized regimens tailored to initial iron status warrant further investigation.

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Publication Details

Journal
The Journal of Maternal-Fetal & Neonatal Medicine
Published
2026-02-11
DOI
https://doi.org/10.1080/14767058.2026.2625570
Primary Topic
Iron Metabolism and Disorders
Type
article
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article

Application of Shengxuening tablets for the prevention of anemia in pregnancy: stratified efficacy analysis based on serum ferritin levels and thalassemia subgroups

XU Hongmei, Xu Jing, Yang Rui, Zeng Yamin et al.
The Journal of Maternal-Fetal & Neonatal Medicine
Iron Metabolism and Disorders
article

Application of Shengxuening tablets for the prevention of anemia in pregnancy: stratified efficacy analysis based on serum ferritin levels and thalassemia subgroups

XU Hongmei, Xu Jing, Yang Rui, Zeng Yamin, Wan Xiaoli, Zhang Lexia
article en

Abstract

SXN tablets effectively ameliorate ID and anemia in both the general obstetric population and pregnant women with the thalassemia trait. The greatest benefit occurs when prophylaxis is initiated at baseline SF ≥30 μg/L. Baseline SF levels positively correlate with therapeutic response, indicating that adequate iron reserves enhance treatment efficacy. Routine, guideline-based iron supplementation should remain a cornerstone of antenatal care; however, individualized regimens tailored to initial iron status warrant further investigation.

The Journal of Maternal-Fetal & Neonatal MedicineVol. 39(1)
People's Hospital of Bishan District (CN)
Good health and well-being
Openalex Percentile: Top 58%
Iron Metabolism and Disorders
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