Macrophage-specific circular RNA circHIPK2, inflammation, and fibrosis after myocardial infarction
Targeting circHIPK2 in macrophages may represent a promising therapeutic strategy for treating inflammatory cardiac conditions and heart failure, potentially leading to the development of RNA-based therapies targeting immune cells in MI treatment.
Authors
- Erika Hilbold (ORCID: https://orcid.org/0000-0001-9808-3729)
- JT Thackeray
- M. Jung
- Arne Schmidt (ORCID: https://orcid.org/0000-0002-8182-1577)
- Angelika Pfanne
- Karina Jansen
- Frank M. Bengel (ORCID: https://orcid.org/0000-0003-4529-7963)
- Marida Sansonetti (ORCID: https://orcid.org/0000-0003-0253-2011)
- Cheng-Kai Huang (ORCID: https://orcid.org/0000-0002-4237-5797)
- Jonas Blume
- Sabrina Thum
- G. Büchler
- Ariane Hai Ha Nguyen
- Sergej Erschow
- Natalie Weber (ORCID: https://orcid.org/0000-0002-2302-1045)
- Kai C. Wollert (ORCID: https://orcid.org/0000-0002-4890-4450)
- Christian Bär (ORCID: https://orcid.org/0000-0001-9276-9383)
- Maximilian Schinke (ORCID: https://orcid.org/0000-0002-0442-2185)
- Bashar Al Soodi
- Ke Xiao
- Annette Just
- Wilson Agyapong
- Lea Oehlsen (ORCID: https://orcid.org/0009-0000-6496-5360)
- Nico Lachmann
- Thomas Thüm
- Melanie Ricke-Hoch
Institutions
- Medizinische Hochschule Hannover (DE)
- Fraunhofer Institute for Toxicology and Experimental Medicine (DE)
Publication Details
- Journal
- European Heart Journal
- Published
- 2026-01-26
- DOI
- https://doi.org/10.1093/eurheartj/ehaf1116
- Citations
- 1
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 22.24