Perioperative Immune Checkpoint Inhibitors Combined with Radical Cystectomy: A Rapid Systematic Review and Meta-analysis

We reviewed studies in patients with muscle-invasive bladder cancer who received immunotherapy around the time of surgery. The results suggest that combining immunotherapy with surgery may offer a benefit, but further research is needed to determine which patients benefit the most and the best timing and combinations of these treatments.

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Publication Details

Journal
European Urology Open Science
Published
2026-02-11
DOI
https://doi.org/10.1016/j.euros.2026.01.016
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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0.00
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article

Perioperative Immune Checkpoint Inhibitors Combined with Radical Cystectomy: A Rapid Systematic Review and Meta-analysis

Navid Roessler, P. Rajwa, Markus von Deimling, Morgan Rouprêt et al.
European Urology Open Science
Bladder and Urothelial Cancer Treatments
article

Perioperative Immune Checkpoint Inhibitors Combined with Radical Cystectomy: A Rapid Systematic Review and Meta-analysis

Navid Roessler, P. Rajwa, Markus von Deimling, Morgan Rouprêt, Margit Fisch, Shahrokh F. Shariat, Shota Inoue, Marcin Miszczyk, Keiichiro Miyajima, David D’Andrea
article en

Abstract

We reviewed studies in patients with muscle-invasive bladder cancer who received immunotherapy around the time of surgery. The results suggest that combining immunotherapy with surgery may offer a benefit, but further research is needed to determine which patients benefit the most and the best timing and combinations of these treatments.

European Urology Open ScienceVol. 85
Al-Ahliyya Amman University (JO), Jikei University School of Medicine (JP), Universität Hamburg (DE), Okayama University (JP), Medical University of Silesia (PL), Cornell University (US), Charles University (CZ), Sorbonne Université (FR), Comprehensive Cancer Center Vienna (AT), Assistance Publique – Hôpitaux de Paris (FR), University Medical Center Hamburg-Eppendorf (DE), Pitié-Salpêtrière Hospital (FR), WSB University (PL), Karl Landsteiner Society (AT), Onco-Urologie Prédictive, Medical University of Vienna (AT), The University of Texas Southwestern Medical Center (US)
Good health and well-being
Openalex Percentile: Top 59%
Bladder and Urothelial Cancer Treatments
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