Semaglutide as adjunctive therapy to catheter ablation in obesity-related paroxysmal atrial fibrillation

Glucagon-like peptide-1 receptor agonist therapy using semaglutide is associated with a reduced risk of AF recurrence in obese patients undergoing AF catheter ablation, indicating its potential as an adjunctive treatment. Further studies are needed to confirm these findings and elucidate the effects of GLP-1RA on AF recurrence.

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Publication Details

Journal
EP Europace
Published
2026-02-01
DOI
https://doi.org/10.1093/europace/euag018
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Semaglutide as adjunctive therapy to catheter ablation in obesity-related paroxysmal atrial fibrillation

Gabriele Negro, Žarko Ćalović, CARLO PAPPONE, Antonio Boccellino et al.
EP Europace
Atrial Fibrillation Management and Outcomes
article

Semaglutide as adjunctive therapy to catheter ablation in obesity-related paroxysmal atrial fibrillation

Gabriele Negro, Žarko Ćalović, CARLO PAPPONE, Antonio Boccellino, Antonio Izzo, Cristiano Ciaccio, Roberto Rondine, Alessandro Fuga, Luigi Giannelli, Davide Antonio Morciano, Alessia Vuturo, Raffaele Salerno, Arianna Garbelli, Luigi Anastasia, Marco Ballarotto, Vincenzo Maiolo
article en

Abstract

Glucagon-like peptide-1 receptor agonist therapy using semaglutide is associated with a reduced risk of AF recurrence in obese patients undergoing AF catheter ablation, indicating its potential as an adjunctive treatment. Further studies are needed to confirm these findings and elucidate the effects of GLP-1RA on AF recurrence.

EP EuropaceVol. 28(2)
Vita-Salute San Raffaele University (IT), IRCCS Policlinico San Donato (IT), Mylan (South Africa) (ZA)
Openalex Percentile: Top 61%
Atrial Fibrillation Management and Outcomes
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Semaglutide as adjunctive therapy to catheter ablation in obesity-related paroxysmal atrial fibrillation — Gabriele Negro, Žarko Ćalović, et al. · EP Europace (2026) | TGRS Research Map | TGRS