Early diagnosis of acute experimental autoimmune myocarditis in mice with preserved left ventricular ejection fraction: a feasibility study based on 9.4 T magnetic resonance

The feasibility of LV strain parameters combined with CMR conventional sequences in identifying EAM in mice at 9.4 T CMR has good reproducibility. For mice with preserved LV ejection fraction, the combination of T2 and GRS can significantly increase the ability to predict EAM within 7 days and provides incremental value as compared to conventional CMR parameters.

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Publication Details

Journal
Cardiovascular Diagnosis and Therapy
Published
2026-02-01
DOI
https://doi.org/10.21037/cdt-2025-500
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Early diagnosis of acute experimental autoimmune myocarditis in mice with preserved left ventricular ejection fraction: a feasibility study based on 9.4 T magnetic resonance

Zhixuan Wen, Qinfang Miao, Chuangwei Wei, Lei Xu et al.
Cardiovascular Diagnosis and Therapy
Viral Infections and Immunology Research
article

Early diagnosis of acute experimental autoimmune myocarditis in mice with preserved left ventricular ejection fraction: a feasibility study based on 9.4 T magnetic resonance

Zhixuan Wen, Qinfang Miao, Chuangwei Wei, Lei Xu, Haikun Qi, Nan Zhang, Yan Chen, Wenjing Zhao, Jiayi Liu
article en

Abstract

The feasibility of LV strain parameters combined with CMR conventional sequences in identifying EAM in mice at 9.4 T CMR has good reproducibility. For mice with preserved LV ejection fraction, the combination of T2 and GRS can significantly increase the ability to predict EAM within 7 days and provides incremental value as compared to conventional CMR parameters.

Cardiovascular Diagnosis and TherapyVol. 16(1)
Capital Medical University (CN), ShanghaiTech University (CN), Beijing Anzhen Hospital (CN), Shanghai Clinical Research Center (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 61%
Viral Infections and Immunology Research
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Early diagnosis of acute experimental autoimmune myocarditis in mice with preserved left ventricular ejection fraction: a feasibility study based on 9.4 T magnetic resonance — Zhixuan Wen, Qinfang Miao, et al. · Cardiovascular Diagnosis and Therapy (2026) | TGRS Research Map | TGRS