The prognostic impact of <i>CDKN2A/B</i> hemizygous deletions in meningioma
Our findings suggest that hemizygous CDKN2A/B deletions overall do not confer worse risks for progression in meningiomas. The signal for segmental deletions may not be locus-specific but just one representation of the generally instable genome of aggressive meningiomas.
Authors
- Sybren L. N. Maas (ORCID: https://orcid.org/0000-0002-8745-4405)
- M. Snuderl
- Dennis Friedel (ORCID: https://orcid.org/0009-0000-5067-3009)
- Areeba Patel (ORCID: https://orcid.org/0000-0003-0374-4227)
- M Preusser
- Thomas Hielscher (ORCID: https://orcid.org/0000-0003-1277-310X)
- Kirsten Göbel (ORCID: https://orcid.org/0009-0006-2117-6381)
- Wenya Linda Bi
- Philipp Sievers
- Abigail K. Suwala
- Andreas von Deimling
- Till Acker
- Michael Weller
- Wolfgang Wick
- Sebastian Brandner
- Felix Sahm
- Franziska M Ippen
Institutions
- University College London Hospitals NHS Foundation Trust (GB)
- German Cancer Research Center (DE)
- University of Zurich (CH)
- Heidelberg University (DE)
- Universitätsklinikum Gießen und Marburg (DE)
- Leiden University Medical Center (NL)
- University Hospital Heidelberg (DE)
- Massachusetts General Hospital (US)
- University Hospital of Zurich (CH)
- National Center for Tumor Diseases (DE)
- Giessen School of Theology (DE)
- Erasmus MC Cancer Institute (NL)
- University College London (GB)
- New York University (US)
- Medical University of Vienna (AT)
- Heidelberg University (US)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1093/neuonc/noag024
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.00