Carbon-based nanomaterials induce ovarian dysfunction via NLRP3 inflammasome-mediated pyroptosis in granulosa cells
These findings reveal a novel mechanism by which carbon-based nanomaterials impair ovarian function through NLRP3 inflammasome-mediated pyroptosis and highlight NLRP3 inhibition as a potential therapeutic strategy for mitigating carbon-based nanomaterials associated ovarian injury.
Authors
- Yun Dai (ORCID: https://orcid.org/0000-0002-1199-9855)
- Simin Wei
- Liru Xue
- Yourong Feng (ORCID: https://orcid.org/0000-0003-1768-0930)
- Chuqing Wu
- Jun Dai
- Weicheng Tang
- Yiqing Song
- Meng Wu
- Shixuan Wang
- Peizhe Zheng
- Dan Chen
- Jingxin Wang
- Yican Guo
Institutions
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jare.2026.02.002
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00