Fatal Overdose, Acute Viral Hepatitis, and Human Immunodeficiency Virus Attributed to Injection Drug Use, Appalachian Region of the United States, 2000–2023
We documented elevated rates of infectious diseases and fatal drug overdose against a background of increased economic distress in the central Appalachian subregions, especially among working-age adults of reproductive age. Interventions to address social determinants of health and expand access to comprehensive integrated medical and substance use disorder treatment, overdose prevention, and syringe services are critical to control this syndemic.
Authors
- Godwin U. Obiri
- Craig Morin
- Rachel Stallings
- Neil Gupta (ORCID: https://orcid.org/0000-0003-3470-5351)
- Tisha Johnson
- Jessica Korona-Bailey (ORCID: https://orcid.org/0000-0002-0314-5171)
- Anne Harwood Peruski (ORCID: https://orcid.org/0000-0001-5765-672X)
- Ami Gandhi
- Carrie Thomas Goetz
- Paula Shoup
- Lucila Zamboni (ORCID: https://orcid.org/0000-0002-1872-4512)
- Stephanie Muhammad
- Danae Bixler (ORCID: https://orcid.org/0000-0003-3140-9530)
- Claire Holiday
- Laura Simone Edison
- K. O. Miller
- Kady Pack (ORCID: https://orcid.org/0009-0009-7776-3325)
- Shaoman Yin
- Premal Bhatt
- Joshua Moore
- Taylor Swankie
- Allison Thomson
- Xueyuan Wang
- Catheryn Morateck
- Dana Quensinberry
- Abdoulaye Diedhiou
- Miracle King
- Carolyne Cody Bennett
- Appalachian Jurisdiction Partners
- Lauren Orkis
Institutions
- Centers for Disease Control and Prevention (US)
- The Centers (US)
- Centers for Disease Control and Prevention (KE)
- Center for Prevention Services (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1093/cid/ciaf730
- Primary Topic
- HIV, Drug Use, Sexual Risk
- Type
- article
- Field-Weighted Citation Impact
- 0.00