Development and Validation of Regression-based Neuropsychological Testing Norms for Peruvian adults to detect HIV-associated Neurocognitive Impairment
Our findings highlight the utility of locally derived norms in detecting subtle cognitive changes among young and middle-aged PWH compared with previously published norms for Spanish-speakers. Application of these norms reveals significant between-group differences that may go undetected using non-local normative data or raw scores. Future efforts should focus on rural norm development and inclusion of individuals with lower educational backgrounds in Peru and other Latin American countries.
Authors
- Patricia Sotolongo
- Valeria Roldán (ORCID: https://orcid.org/0009-0009-6020-2791)
- Jane She
- Kimberly P. Enders
- P. Mario García
- Marleny Nolasco
- Sofía Tovar-Ramirez (ORCID: https://orcid.org/0000-0002-9829-2739)
- Elena Tsoy
- Mónica María Díaz
- Victor Valcour
- Maria Marquine
- Yamile Rodriguez-Angeles
- Yating Zou
- Fernando Mejia
Institutions
- University of North Carolina at Chapel Hill (US)
- Duke University (US)
- University of California, San Francisco (US)
- Universidad Peruana Cayetano Heredia (PE)
- Utah State Hospital (US)
- Hospital Nacional Cayetano Heredia (PE)
- Global Brain Health Institute (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-02-11
- DOI
- https://doi.org/10.64898/2026.02.09.26345550
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00