Computational modeling and experimental validation for developed non-hormonal <i>in-situ</i> reversible cervical contraceptive plugs
<i>Ex-vivo</i> studies have confirmed sperm immobilisation and morphological changes. <i>In-vivo</i> studies achieved 100% contraception without mucosal irritation, and fertility was restored post study. Stability studies indicated robust formulation properties. The developed cervical plug offers a non-hormonal contraceptive option that is reversible, effective, and safe.
Authors
- Keerthana Kunchakuri
- B. V. Basavaraj (ORCID: https://orcid.org/0000-0003-4726-9528)
- Shwetha Krishnamurthy
Institutions
- M S Ramaiah University of Applied Sciences (IN)
Publication Details
- Journal
- The European Journal of Contraception & Reproductive Health Care
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1080/13625187.2026.2625131
- Primary Topic
- Reproductive Health and Contraception
- Type
- article
- Field-Weighted Citation Impact
- 0.00