Real-world Study of Three-gas Breath Testing Nationwide and the Association With Symptoms

H2, CH4, and H2S are associated with unique symptoms: CH4 with constipation and H2S with diarrhea and a greater overall symptom severity. Glucose appears less sensitive than lactulose, suggesting it could potentially miss some symptomatic patients.

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Publication Details

Journal
Journal of Clinical Gastroenterology
Published
2026-02-02
DOI
https://doi.org/10.1097/mcg.0000000000002326
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
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article

Real-world Study of Three-gas Breath Testing Nationwide and the Association With Symptoms

Ruchi Mathur, Mohamad Rashid, Daniel Brimberry, Ava Hosseini et al.
Journal of Clinical Gastroenterology
Gastrointestinal motility and disorders
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Real-world Study of Three-gas Breath Testing Nationwide and the Association With Symptoms

Ruchi Mathur, Mohamad Rashid, Daniel Brimberry, Ava Hosseini, Joo Lijin, Ali Rezaie, Linda Nguyen, Mark Pimentel, Matthew Mitcho, Darren Brenner, Fabrice Wilfong, David Richardson, Gabriela Leite
article en

Abstract

H2, CH4, and H2S are associated with unique symptoms: CH4 with constipation and H2S with diarrhea and a greater overall symptom severity. Glucose appears less sensitive than lactulose, suggesting it could potentially miss some symptomatic patients.

Journal of Clinical Gastroenterology
Northwestern University (US), Cedars-Sinai Medical Center (US), UNC/NCSU Joint Department of Biomedical Engineering (US), Northwestern Medicine (US), Stanford University (US)
Openalex Percentile: Top 58%
Gastrointestinal motility and disorders
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Real-world Study of Three-gas Breath Testing Nationwide and the Association With Symptoms — Ruchi Mathur, Mohamad Rashid, et al. · Journal of Clinical Gastroenterology (2026) | TGRS Research Map | TGRS