Acute intermittent hemodialysis management: a single center experience

This retrospective study evaluated prognostic factors affecting outcomes in patients with acute kidney injury (AKI) treated with acute intermittent hemodialysis (IHD). Medical records of 193 patients treated between 2014 and 2024 were reviewed. Patients were categorized as recovered, deceased, chronic kidney disease without dialysis (CKD-ND), or chronic kidney disease with dialysis (CKD-D). The main indications for dialysis were hypervolemia (64.8%) and uremia (24.9%). Overall mortality was 50.8%, while 23.8% recovered, 21.2% developed CKD, and 4.1% became dialysis-dependent. Significant differences among outcome groups were found in age and serum concentration of serum creatinine, urea, sodium, phosphorus, calcium, C-reactive protein (CRP), albumin. Multivariate logistic regression analysis identified lower creatinine and calcium levels, as well as higher sodium, urea, and CRP concentrations, as independent predictors of mortality. In conclusion, our findings highlight the prognostic importance of biochemical and inflammatory markers in AKI patients undergoing IHD. Early identification and correction of electrolyte and inflammatory disturbances may improve patient outcomes.